Zelboraf Side Effects

Studies on the potential side effects of Zelboraf have shown that people taking this medicine may develop problems like hair loss, joint pain, and fatigue. There are also several potentially serious problems that may occur. Make sure to contact your healthcare provider right away if you develop blurry vision, any skin changes, or other potentially serious problems.

An Introduction to Zelboraf Side Effects

Just like any medicine, Zelboraf™ (vemurafenib) can cause side effects. Like most cancer medications, the side effects can be significant. Although not everyone who takes this medication will have problems, many people will experience some type of side effect during Zelboraf treatment. Talk to your healthcare provider about ways to manage these side effects.
 
(This article covers many, but not all, of the possible side effects with Zelboraf. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects With Zelboraf

Zelboraf has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Zelboraf were carefully documented and compared to side effects that occurred in people taking another anticancer medication. As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the other medicine.
 
In these studies, the most common Zelboraf side effects included:
 
  • Joint pain -- in up to 53 percent of people
  • Hair loss -- up to 45 percent
  • Fatigue -- up to 38 percent
  • Rash -- up to 37 percent
  • Nausea -- up to 35 percent
  • Sensitivity to the sun -- up to 33 percent
  • Diarrhea -- up to 28 percent
  • Skin problems and growths, such as dry skin, thickened patches of skin, and warts -- up to 24 percent
  • Itching -- up to 23 percent
  • Headaches -- up to 23 percent.
 
Other common side effects, occurring in 8 to 19 percent of people, included:
 
  • Fever
  • Pain, including general body aches, back pain, and muscle pain
  • Vomiting
  • Decreased appetite
  • Swelling of the arms, hands, legs, ankles, and feet
  • Skin redness or rash
  • Changes in taste
  • Constipation
  • Lack of strength or weakness
  • Sunburn
  • Coughing.
 
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Zelboraf Medication Information

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