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Clinical Effects

Studies have evaluated Sylatron for malignant melanoma. In one study, people who received Sylatron injections weekly after surgery had, on average, about 34.8 months before a relapse. Similar people who were not given Sylatron after surgery had 25.5 months before a relapse, on average. While these results were promising, no difference was seen in survival between the two groups.

When and How to Use It

Some general considerations to keep in mind during treatment with Sylatron include the following:
  • Sylatron comes as an injection. It is injected subcutaneously (just under the skin) once a week for up to five years.
  • Use Sylatron at the same time each week. Your healthcare provider may recommend taking acetaminophen (Tylenol®) before each dose.
  • Each Sylatron vial is for a single use only. If your dose is less than the full vial, any unused portion must be discarded; it cannot be saved for later.
  • It is best to inject Sylatron into areas of the skin that have a layer of fat underneath. This includes the thigh, the outer upper arm, or stomach (away from the navel). Try to rotate the injection sites; do not inject in the same place twice in a row.
  • Make sure your healthcare provider teaches you exactly how to inject Sylatron. This includes how to:


    • How to prepare the skin
    • How to prepare and mix the injection
    • How to inject the medication
    • What to do with your used needles (this may vary, depending on the local laws and regulations).

If you are not comfortable with any part of the process, please let your healthcare provider know.

  • For the medication to work properly, it must be used as prescribed.
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Sylatron Medication Information

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