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Proleukin Warnings and Precautions

Your healthcare provider will have to perform certain tests to make sure you are a good candidate to receive Proleukin. Warnings with this chemotherapy drug include safety precautions for people with heart problems, lung disease, and diabetes. In addition, there are potentially dangerous drug interactions that may occur. Risks with this drug also apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving Proleukin® (aldesleukin) if you have:
  • Heart problems, such as congestive heart failure or an abnormal heartbeat (an arrhythmia)
  • Ever had an abnormal heart stress test
  • A history of a heart attack or chest pain (angina)
  • Lung disease, such as asthma or chronic obstructive pulmonary disease (COPD), or have ever had an abnormal lung function test
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Any central nervous system problem
  • Had an organ transplant
  • An autoimmune or inflammatory condition, such as Crohn's disease or arthritis
  • Diabetes
  • Thyroid problems
  • A current infection
  • A history of abdominal (stomach) or intestinal bleeding
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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Proleukin Medication Information

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