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Proleukin Uses

The approved uses of Proleukin include the treatment of cancer of the skin or kidneys that has spread to other areas of the body. It is approved only for adults age 18 and older. There are also some unapproved, or off-label, uses for this medication, such as treating HIV, colorectal cancer, and non-Hodgkin's lymphoma.

What Is Proleukin Used For?

Proleukin® (aldesleukin) is a prescription anticancer medication. It is sometimes referred to as interleukin-2, or IL-2. Proleukin is approved to treat the following types of cancer:
This drug is considered an immunotherapy product, which is a form of treatment that uses the body's own immune system to fight cancer. Proleukin is used when these cancers have metastasized, which means they have spread beyond the original site to other areas of the body.

Using Proleukin for the Treatment of Metastatic Renal Cell Carcinoma

Renal cell carcinoma (RCC) occurs when cancer cells develop in the lining of small tubes (called tubules) in the kidneys. Although there are other types of kidney cancer, RCC is the most common.
The exact cause of kidney cancer is unknown. Also, no one knows why one person will get kidney cancer and another person will not. However, research has shown that certain risk factors can increase the chance of developing the disease. Some of the risk factors that increase the chance of developing kidney cancer include but are not limited to:
(See Kidney Cancer Risk Factors for more information about these and other risk factors for kidney cancer.)
Proleukin is one of several treatment options for RCC, and treatment often varies by stage of the disease (see Kidney Cancer Treatment By Stage). As stated earlier, the medication is approved to treat RCC that has progressed beyond the kidneys to other areas of the body. Metastatic RCC is also sometimes called advanced kidney cancer, stage IV kidney cancer, or late-stage kidney cancer.
Proleukin is not effective for everyone. However, in clinical trials 7 percent of people, on average, had no evidence of cancer for 7 to over 131 months after treatment with Proleukin.
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Proleukin Medication Information

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