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Mekinist Side Effects

Serious Side Effects

Some Mekinist side effects are potentially serious and should be reported to your healthcare provider immediately. Signs of these potential reactions include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Any rash, even if not accompanied by other symptoms (since Mekinist can cause dangerous problems that start with a rash)
  • Signs of a blood clot in the arms, legs, or lungs, such as shortness of breath, chest pain, or arm or leg swelling
  • Signs of heart problems, such as:
    • Swelling in the legs, ankles, or feet
    • A sudden, unexplained weight gain
    • An irregular, fast, or forceful heartbeat
    • Lightheadedness, dizziness, or fainting
    • Shortness of breath
  • Changes in vision, such as:
    • Blurred vision
    • Loss of vision
    • Seeing halos
    • Seeing colored dots
  • New or worsening shortness of breath or cough
  • Any redness, swelling, peeling, sores, or rash on the skin, hands, or feet
  • High blood pressure
  • High blood sugar
  • Abnormal bleeding or bruising
  • Extreme tiredness or fatigue
  • Any new skin malignancies or tumors anywhere on the body
  • A fever (as this can be the start of a very serious reaction)
  • Any unusual muscle pain.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using Mekinist or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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