Skin Cancer Home > Solaraze Gel Warnings and Precautions

Before taking Solaraze Gel, let your healthcare provider know if you have certain medical conditions, such as asthma, a bleeding problem, or high blood pressure. Warnings and precautions with Solaraze Gel also relate to things such as potential drug interactions and the safety of using the drug if you are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Using Solaraze Gel?

You should talk with your healthcare provider prior to taking Solaraze® Gel (diclofenac gel) if you have:
Also let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Solaraze Gel Warnings and Precautions

Some warnings and precautions to be aware of with Solaraze Gel include:
  • Even though this medication is a gel that is applied to the skin, some of the medication is absorbed into the bloodstream. Therefore, all of the standard warnings and precautions with other nonsteroidal anti-inflammatory drugs (NSAIDs) probably apply to Solaraze Gel as well.
  • NSAIDs have been linked to cardiovascular events, such as heart attack or stroke. People who have cardiovascular disease or cardiovascular risk factors appear to be at greater risk. 
Be sure to call 911 if you notice heart attack symptoms or stroke symptoms such as:
    • Chest pain
    • Shortness of breath
    • Weakness
    • Slurring of speech.


  • All NSAIDs, including Solaraze Gel, may cause congestive heart failure or fluid retention. Contact your healthcare provider if you notice unexplained weight gain or swelling while taking this drug. Also, Solaraze Gel should be used with caution in people with heart failure.
  • NSAIDs have been reported to cause problems in the stomach and intestines, including bleeding (known as gastrointestinal bleeding), stomach ulcers, or holes in the stomach or intestines (called perforations). These problems can lead to serious complications or even loss of life. Contact your healthcare provider immediately if you experience any signs or symptoms of stomach ulcers or bleeding, including:


    • Abdominal (stomach) pain
    • Indigestion
    • Black, tarry stools
    • Vomiting blood. 
It is important to understand that Solaraze Gel can cause these problems, even though it is not taken by mouth.
  • Solaraze Gel can interact with certain medications (see Solaraze Gel Drug Interactions).
  • In general, Solaraze Gel is not recommended for people with severe liver or kidney disease.
  • NSAIDs, including Solaraze Gel, have been reported to cause allergic reactions. Seek emergency medical attention immediately if you notice things such as difficulty breathing or swelling of the face and throat.
  • It is possible that Solaraze Gel could worsen asthma, especially in people with aspirin-sensitive asthma.
  • Avoid prolonged, unprotected sun exposure while using this medication. Because Solaraze is used to treat precancerous, sun-damaged skin, people who use the medication should always use appropriate sun protection.
  • Solaraze Gel is a pregnancy Category B medicine, meaning that it is considered relatively safe for use during pregnancy, although the full risks are currently unknown (see Solaraze Gel and Pregnancy for more information).
  • It is unknown if Solaraze Gel passes through breast milk. Therefore, if you are breastfeeding a child, check with your healthcare provider (or your child's healthcare provider) before using Solaraze Gel (see Solaraze Gel and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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