Skin Cancer Home > Proleukin Drug Interactions

Combining Proleukin with blood pressure medications, antidepressants, or certain other drugs may cause negative interactions. Some of these adverse reactions may include infections, heart problems, and kidney damage. To avoid complications, make sure you talk to your healthcare provider about any medications, vitamins, or supplements you are taking before starting treatment with Proleukin.

An Overview of Interactions With Proleukin

Proleukin® (aldesleukin) can potentially react with a number of other products. Some of the drugs that can lead to interactions with Proleukin include but are not limited to:
 
  • Aminoglycoside antibiotics, such as:
 
    • Amikacin (Amikin®)
    • Gentamicin
    • Kanamycin (Kantrex®)
    • Neomycin (Neo-Fradin®)
    • Streptomycin
    • Tobramycin
 
 
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
  • Medications that cause drowsiness, such as:
 
 
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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