As a type of chemotherapy drug, DTIC-Dome® (dacarbazine) is prescribed to treat malignant melanoma that has spread to other areas of the body (metastasized). It is also approved for use in combination with other medications to treat Hodgkin's disease. It comes as an injection that is given into a vein once a day for 5 to 10 days, followed by a break in treatment.
When undergoing therapy with DTIC-Dome, you should understand the potential risks associated with this medicine. For example, this medication may not be safe for use in people with certain allergies or those taking certain medications or herbal supplements. Also, people who have kidney disease, liver disease, or other medical issues should discuss whether DTIC-Dome is an appropriate medicine for their situation.
(Click DTIC-Dome for a closer look at this chemotherapy drug, including an explanation of how the drug works and a list of helpful dosing tips.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 13, 2012.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
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