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Aldara Mechanism of Action

Aldara® (imiquimod cream) is a prescription medicine used to treat certain skin conditions, such as genital or perianal warts, actinic keratosis, and superficial basal cell carcinoma.
It is not exactly known how Aldara works. However, it may work by activating the immune system. During clinical studies, Aldara was significantly more effective than a placebo cream that did not contain any active ingredients. In these studies, 44 percent to 46 percent of people using Aldara had complete disappearance of their actinic keratoses, compared to only 3 percent to 4 percent of people using the placebo.
In studies of the drug for superficial basal cell carcinoma, 75 percent of people using Aldara had a complete disappearance of the cancer, compared with just 2 percent of people using the placebo cream.
(To learn more about this drug's mechanism of action, click Aldara. This article covers several topics, such as potential side effects, dosing guidelines, and general safety precautions to discuss with your healthcare provider before beginning treatment.)
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